Usefulness of salivary sialic acid as a tumor marker in tobacco chewers with oral cancer
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چکیده
منابع مشابه
Sialic acid as a tumor marker.
The term sialic acid is used to describe derivatives of neuraminic acid, where the amino group of neuraminic acid is substituted by either an acetyl or glycolyl group. The unique structural features of the molecule, which includes a negative charge owing to a carboxyl group, enables it to play a role in cellular functions, such as transport of positively charged compounds, cell-to-cell repulsio...
متن کاملLipid-bound sialic acid as a tumor marker.
Significant elevations in plasma/serum lipid bound sialic acid (LSA) concentrations have been documented in patients with malignant diseases. Initial studies indicate that LSA may be a useful marker in cancer of the prostate, bladder, breast, lung, colon, ovary and in leukemia, lymphoma, Hodgkins disease and melanoma. The data suggest that the LSA test lacks the required sensitivity and specifi...
متن کاملsalivary sialic acid levels in smokeless tobacco users
conclusions salivary free and total sialic acid, and total protein were higher in the paan consumers compared to non-consumers. due to the carcinogenic effect of smokeless tobacco, measurement of these parameters in saliva may be useful in early detection of oral cancer. results the concentration of salivary free sialic acid (23.21 ± 18.98 mg/l) was significantly increased in paan consumers. th...
متن کاملSalivary Sialic Acid Levels in Smokeless Tobacco Users
BACKGROUND Smokeless tobacco chewing is one of the known risk factors for oral cancer. It is consumed widely by residents of southeastern Iran. OBJECTIVES In this study, salivary free and total sialic acid, and total protein were compared in paan consumers and non-consumers. PATIENTS AND METHODS In this cross-sectional study, unstimulated saliva of 94 subjects (44 paan consumers and 50 non-...
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Objective(s)The key transcriptional regulator Oct4 is one of the self-renewal and differentiation-related factors in cancer stem cells, where it maintains "stemness" state. Cancer stem cells have been identified in a variety of solid malignancies. They are a small population of tumor cells with stem cell characteristics, which are a likely cause of relapse in cancer patients. Due to high incide...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Therapeutics
سال: 2020
ISSN: 0973-1482
DOI: 10.4103/jcrt.jcrt_337_19